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VideoClinical Research

Psilocybin for Alcohol Use Disorder: The Randomized Trial

Inside the randomized clinical trial that tested psilocybin therapy against a placebo for people with alcohol use disorder.

psilocybinalcohol use disorderaddictionpsychedelic therapyclinical researchpsilocybe cubensis

Source Research Papers

Citations in APA 7 format. All studies were sourced from peer-reviewed journals via Google Scholar. Unfamiliar terms? See the plain-language glossary →

Bogenschutz, M. P., Ross, S., Bhatt, S., Baron, T., Forcehimes, A. A., Laska, E., Mennenga, S. E., O'Donnell, K., Owens, L. T., Podrebarac, S., Rotrosen, J., Tonigan, J. S., & Worth, L. (2022). Percentage of heavy drinking days following psilocybin-assisted psychotherapy vs placebo in the treatment of adult patients with alcohol use disorder: A randomized clinical trial. JAMA Psychiatry, 79(10), 953–962. https://doi.org/10.1001/jamapsychiatry.2022.2096

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Bottom line

In a rigorous trial of nearly 100 adults, psilocybin plus therapy cut heavy-drinking days far more than a placebo — some of the strongest evidence yet that it can help with alcohol use disorder.

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