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Home/Research Hub/Psilocybin & Obsessive-Compulsive Disorder, Explained
VideoClinical Research

Psilocybin & Obsessive-Compulsive Disorder, Explained

A short explainer on what researchers found when they gave psilocybin to people with treatment-resistant OCD.

psilocybinOCDobsessive-compulsive disorderpsychedelic therapyclinical researchpsilocybe cubensis

Source Research Papers

Citations in APA 7 format. All studies were sourced from peer-reviewed journals via Google Scholar.

Moreno, F. A., Wiegand, C. B., Taitano, E. K., & Delgado, P. L. (2006). Safety, tolerability, and efficacy of psilocybin in 9 patients with obsessive-compulsive disorder. The Journal of Clinical Psychiatry, 67(11), 1735–1740. https://doi.org/10.4088/jcp.v67n1110

🟡 Early evidenceSupportive
Bottom line

In an early test with nine people who had hard-to-treat OCD, psilocybin was safe and briefly reduced symptoms — promising enough to justify larger studies.

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