Psilocybin for PTSD: Inside the First Single-Dose Trial
A look at an early trial testing whether a single dose of psilocybin is safe for people with PTSD.
Source Research Papers
Citations in APA 7 format. All studies were sourced from peer-reviewed journals via Google Scholar.
McGowan, N. M., Rucker, J. J., Yehuda, R., Agrawal, M., Modlin, N. L., Simmons, H., Tofil-Kaluza, A., Das, S., & Goodwin, G. M. (2025). Investigating the safety and tolerability of single-dose psilocybin for post-traumatic stress disorder: A nonrandomized open-label clinical trial. Journal of Psychopharmacology, 40(1), 139–148. https://doi.org/10.1177/02698811251362390
An early study (where everyone knew they were getting the drug) found a single psilocybin dose was generally safe for PTSD and showed signs of improvement — bigger controlled trials are still needed.
Shop Related Spores
Laboratory-grade Psilocybe cubensis spore syringes for microscopy research.