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Home/Research Hub/Psilocybin & Quitting Smoking: A Pilot Study
VideoClinical Research

Psilocybin & Quitting Smoking: A Pilot Study

How a small pilot study used psilocybin to help long-term smokers quit, with surprising results.

psilocybinsmoking cessationtobacco addictionpsychedelic therapyclinical researchpsilocybe cubensis

Source Research Papers

Citations in APA 7 format. All studies were sourced from peer-reviewed journals via Google Scholar.

Johnson, M. W., Garcia-Romeu, A., Cosimano, M. P., & Griffiths, R. R. (2014). Pilot study of the 5-HT2A receptor agonist psilocybin in the treatment of tobacco addiction. Journal of Psychopharmacology, 28(11), 983–992. https://doi.org/10.1177/0269881114548296

🟡 Early evidenceSupportive
Bottom line

In a small quit-smoking program, 12 of 15 long-term smokers were still smoke-free six months after their psilocybin sessions — a striking result, but with no comparison group.

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